Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 7/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.40 |
| ▸ | ALOX15B | O15296 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28226926 | 0.84 | L3MBTL1 (0.57) | MAPK9MAPK10KDRP2RX4CYP1A2 | |
| SCHEMBL8698318 | 0.84 | MAPK9 (0.48) | MAPK9MAPK10KDRP2RX4CYP1A2 | |
| Benzene SCHEMBL27839441 | 0.83 | MAPK9 (0.54) | MAPK9MAPK10KDRP2RX4CYP1A2 | |
| SCHEMBL528245 | 0.83 | MAPK9 (0.54) | MAPK9MAPK10KDRP2RX4CYP1A2 | |
| SCHEMBL17743635 | 0.82 | MAPK9 (0.51) | MAPK9MAPK10TAAR1KDRP2RX4 | |
| SCHEMBL28237433 | 0.82 | HSD11B1 (0.49) | MAPK9MAPK10KDRP2RX4CYP1A2 | |
| Hydrochloric Acid SCHEMBL27683877 | 0.81 | MAPK9 (0.53) | MAPK9MAPK10KDRP2RX4CYP1A2 | |
| SCHEMBL26562756 | 0.80 | KDR (0.55) | MAPK9MAPK10KDRP2RX4SMN1; SMN2 | |
| SCHEMBL27721362 | 0.80 | MAPK9 (0.47) | MAPK9MAPK10KDRP2RX4CYP1A2 | |
| SCHEMBL20918400 | 0.79 | MAPK9 (0.51) | MAPK9MAPK10KDRP2RX4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106238098-B | A kind of preparation method and its catalyst for preparing of 1,2,4,5- tetra- substituted ramification of imidazole | 马鞍山市泰博化工科技有限公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-106238098-A | The preparation method of a kind of 1,2,4,5 four substituted ramification of imidazole and catalyst for preparing thereof | 马鞍山市泰博化工科技有限公司 | 2016-12-21 | — | — | CN | disclosed |