Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865850 | 0.84 | GSK3B (0.47) | HCAR3HPGDSKDM4EALDH1A1ALOX15 | |
| SCHEMBL19049506 | 0.84 | HCAR3 (0.55) | HCAR3MAPTSMN1; SMN2L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL9670823 | 0.83 | HCAR3 (0.45) | HCAR3HPGDSSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28865950 | 0.83 | HCAR3 (0.49) | HCAR3HPGDSKDM4EALDH1A1ALOX15 | |
| SCHEMBL12734188 | 0.81 | HCAR3 (0.49) | HCAR3HPGDSMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL23149714 | 0.80 | KMT2A (0.43) | HCAR3HPGDSMAPTSMN1; SMN2KDM4E | |
| SCHEMBL30786543 | 0.80 | KMT2A (0.43) | HCAR3HPGDSMAPTSMN1; SMN2KDM4E | |
| SCHEMBL185127 | 0.79 | HCAR3 (0.65) | HCAR3MAPTKDM4EALDH1A1ALOX15 | |
| SCHEMBL27855599 | 0.78 | CA12 (0.50) | HCAR3MAPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1778519 | 0.78 | HCAR3 (0.46) | HCAR3HPGDSMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106068265-A | Dihydropyridone MGAT2 inhibitors for the treatment of metabolic disorders | 百时美施贵宝公司 | 2016-11-02 | — | — | CN | disclosed |