Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111819 | 0.83 | HCAR3 (0.51) | HCAR3HPGDSKDM4EALDH1A1ALOX15 | |
| SCHEMBL16865850 | 0.81 | GSK3B (0.47) | HCAR3HPGDSKDM4EALDH1A1ALOX15 | |
| SCHEMBL185127 | 0.80 | HCAR3 (0.65) | HCAR3KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL23149714 | 0.80 | KMT2A (0.43) | HCAR3HPGDSKDM4EALDH1A1TRPV1 | |
| SCHEMBL30786543 | 0.80 | KMT2A (0.43) | HCAR3HPGDSKDM4EALDH1A1TRPV1 | |
| Hydrochloric Acid SCHEMBL9670823 | 0.80 | HCAR3 (0.45) | HCAR3HPGDSKDM4EALDH1A1ALOX15 | |
| SCHEMBL27597231 | 0.79 | ERCC5 (0.46) | KDM4EALDH1A1TRPV1MAPK8 | |
| SCHEMBL12734188 | 0.78 | HCAR3 (0.49) | HCAR3HPGDSKDM4EALDH1A1ALOX15 | |
| SCHEMBL3978664 | 0.78 | HPGDS (0.50) | HCAR3HPGDSKDM4EALDH1A1P4HTM | |
| SCHEMBL1872796 | 0.76 | MAPK1 (0.61) | HCAR3HPGDSKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658991-A | 3,5- disubstituted methyls pyrazolo [1,5-a] pyrimidine -7- phenates analogs and derivatives preparation methods and purposes | 辽宁利锋科技开发有限公司 | 2018-10-16 | — | — | CN | disclosed |