Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28679175 | 0.80 | KMT2A (0.49) | KMT2ASCN5ACA12CA1CA2 | |
| SCHEMBL28111866 | 0.79 | KMT2A (0.35) | KMT2AATMPOLBAPEX1CA12 | |
| SCHEMBL8738354 | 0.78 | ESR1 (0.44) | KMT2APOLBALOX15GAAMAPT | |
| SCHEMBL27721743 | 0.77 | KMT2A (0.44) | KMT2APOLBCA12CA1CA2 | |
| SCHEMBL16942547 | 0.76 | KMT2A (0.38) | KMT2AATMPOLBAPEX1ALOX15 | |
| SCHEMBL15548526 | 0.75 | KMT2A (0.49) | KMT2AATMPOLBAPEX1ALOX15 | |
| SCHEMBL15447053 | 0.75 | LMNA (0.45) | KMT2AATMPOLBAPEX1ALOX15 | |
| SCHEMBL4090840 | 0.73 | TDP1 (0.48) | KMT2AATMKDM4EL3MBTL1HPGD | |
| SCHEMBL7538049 | 0.73 | PIM1 (0.53) | KMT2APOLBGAAKDM4EMAPT | |
| SCHEMBL15447054 | 0.73 | MAPT (0.43) | KMT2AATMPOLBAPEX1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061943-B | It can be used as the bicyclic pyrrole derivatives of the agonist of GPR120 | 詹森药业有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-106061943-A | Bicyclic pyrrole derivatives useful as agonists of GPR120 | 詹森药业有限公司 | 2016-10-26 | — | — | CN | disclosed |