Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111862 | 0.79 | KMT2A (0.38) | KMT2AL3MBTL1KDM4EATMPOLB | |
| SCHEMBL9689656 | 0.78 | FFAR1 (0.38) | MAPT | |
| SCHEMBL8738354 | 0.77 | ESR1 (0.44) | KMT2AL3MBTL1POLBALOX15LMNA | |
| SCHEMBL28784902 | 0.76 | KMT2A (0.36) | KMT2AL3MBTL1KDM4EATMPOLB | |
| SCHEMBL27820633 | 0.76 | KDM4E (0.37) | KMT2AL3MBTL1KDM4EATMPOLB | |
| SCHEMBL27721743 | 0.76 | KMT2A (0.44) | KMT2AL3MBTL1KDM4EPOLBCA12 | |
| SCHEMBL15548526 | 0.74 | KMT2A (0.49) | KMT2AL3MBTL1KDM4EATMPOLB | |
| SCHEMBL27685965 | 0.74 | ALDH1A1 (0.46) | KMT2AL3MBTL1KDM4EPOLBLMNA | |
| SCHEMBL15447053 | 0.73 | LMNA (0.45) | KMT2AL3MBTL1KDM4EATMPOLB | |
| SCHEMBL25797751 | 0.73 | ALOX15 (0.50) | KMT2AKDM4EATMALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061943-A | Bicyclic pyrrole derivatives useful as agonists of GPR120 | 詹森药业有限公司 | 2016-10-26 | — | — | CN | disclosed |