SCHEMBL4090840

SCHEMBL4090840

CCC(C)C(=O)Oc1ccccc1C

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
ATM Q13315 1/20 0.48
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 2/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.44
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
HPGD P15428 1/20 0.41
PPARG P37231 1/20 0.41
BCHE P06276 1/20 0.41
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15548526 0.89 KMT2A (0.49) TDP1L3MBTL1ATMKDM4EALDH1A1
SCHEMBL4084312 0.87 TDP1 (0.49) TDP1L3MBTL1ATMKDM4EALDH1A1
SCHEMBL14578008 0.84 KMT2A (0.43) TDP1L3MBTL1ATMKDM4EALDH1A1
SCHEMBL15547525 0.83 PTGS2 (0.47) TDP1L3MBTL1KDM4EALDH1A1KMT2A
SCHEMBL17459128 0.83 L3MBTL1 (0.44) L3MBTL1ATMKDM4EALDH1A1HTT
SCHEMBL27721743 0.83 KMT2A (0.44) TDP1L3MBTL1KDM4EALDH1A1HTT
SCHEMBL15547890 0.83 ALOX15 (0.47) L3MBTL1ATMKDM4EALDH1A1KMT2A
SCHEMBL4085152 0.83 KMT2A (0.49) L3MBTL1ATMKDM4EALDH1A1KMT2A
SCHEMBL1261877 0.82 MEN1 (0.51) TDP1L3MBTL1ATMKDM4EALDH1A1
SCHEMBL7751175 0.81 TDP1 (0.47) TDP1L3MBTL1ATMKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10895840-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-01-19 US disclosed
US-20200159135-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-05-21 US disclosed
US-10539888-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10042273-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-08-07 US disclosed
US-20170108790-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-04-20 US disclosed
US-9599915-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-20090186138-A1 Method of Flavoring GIVAUDAN SA (CH) 2009-07-23 US disclosed
CN-1918133-A Alpha-4 integrin mediated cell adhesion inhibitors for the treatment or prevention of inflammatory diseases TANABE SEIYAKU CO (JP) 2007-02-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186138-A1 Method of Flavoring TAS2R5, TAS2R50, TAS2R10 TDP1 4513/4885L3MBTL1 3164/4885ATM 2702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.