SCHEMBL28111886

SCHEMBL28111886

CC(C)c1cc(-c2cc(C(C)C)c(O)c(C(C)C)c2)c(N)c(C(C)C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
GABRA1 P14867 6/20 0.52
GABRB2 P47870 3/20 0.52
GABRB1 P18505 5/20 0.41
FABP3 P05413 2/20 0.38
FABP4 P15090 2/20 0.38
FABP5 Q01469 1/20 0.37
GSR P00390 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HIF1A Q16665 2/20 0.35
FAAH O00519 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
GABRG2 P18507 1/20 0.35
PTGS1 P23219 1/20 0.35
SLC6A2 P23975 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94533 0.79 GABRA1 (0.77) CA1CA2GABRA1GABRB2GABRB1
SCHEMBL15064751 0.77 GABRA1 (0.68) CA1CA2GABRA1GABRB2GABRB1
Ammonia Solution, Strong SCHEMBL28098766 0.77 GABRA1 (0.74) CA1CA2GABRA1GABRB2GABRB1
SCHEMBL9229754 0.76 CA1 (0.64) CA1CA2GABRA1GABRB2GABRB1
SCHEMBL19621818 0.75 CA1 (0.77) CA1CA2GABRA1GABRB2GABRB1
SCHEMBL3440745 0.74 GABRA1 (0.50) CA1CA2GABRA1GABRB2GABRB1
SCHEMBL19972010 0.74 GABRA1 (0.63) CA1CA2GABRA1GABRB2GABRB1
SCHEMBL26521897 0.74 GABRA1 (0.63) CA1CA2GABRA1GABRB2GABRB1
SCHEMBL275427 0.72 CA1 (1.00) CA1CA2GABRA1GABRB2GABRB1
SCHEMBL20432611 0.70 GABRA1 (0.47) CA1CA2GABRA1GABRB2GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104557532-B Bigeminy benzene derivative and its application 西安力邦制药有限公司 2017-03-01 CN disclosed