SCHEMBL28111954

SCHEMBL28111954

C=CC=Cc1cccc(C)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.37
ATM Q13315 1/20 0.37
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.35
CDK4 P11802 1/20 0.33
CCND1 P24385 1/20 0.33
MAPT P10636 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
ADRB1 P08588 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
RAB9A P51151 2/20 0.31
KDM4E B2RXH2 1/20 0.31
APOBEC3A P31941 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18434317 1.00 TRPA1 (0.37) TRPA1ATMTSHRALDH1A1CDK4
SCHEMBL29800531 0.83 ALDH1A1 (0.48) TSHRALDH1A1CDK4CCND1MAPT
SCHEMBL2836136 0.83 ALDH1A1 (0.48) TSHRALDH1A1CDK4CCND1MAPT
SCHEMBL12802018 0.83 ALDH1A1 (0.48) TSHRALDH1A1CDK4CCND1MAPT
SCHEMBL14558034 0.83 ALDH1A1 (0.48) TSHRALDH1A1CDK4CCND1MAPT
SCHEMBL6546426 0.82 TRPA1 (0.46) TRPA1ATMTSHRALDH1A1CYP1A2
SCHEMBL4318496 0.82 TRPA1 (0.46) TRPA1ATMTSHRALDH1A1CYP1A2
SCHEMBL27413678 0.81 MAOB (0.41) TRPA1TSHRALDH1A1MAPTSMN1; SMN2
SCHEMBL23707435 0.80 NFE2L2 (0.40) ACHE
SCHEMBL13645541 0.80 APP (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209683-B Method for delivering non-aromatic solutions to a polymerization reactor 埃克森美孚化学专利公司 2025-05-13 CN disclosed
CN-117377703-A Two-phase polymerization process 埃克森美孚化学专利公司 2024-01-09 CN disclosed
CN-117062846-A Metal complex catalyst for olefin polymerization 阿朗新科荷兰有限公司 2023-11-14 CN disclosed
CN-116601160-A Improved process for preparing catalysts from in situ formed aluminoxanes 埃克森美孚化学专利公司 2023-08-15 CN disclosed
CN-112218900-B Catalyst system comprising two hafnocene catalyst compounds 埃克森美孚化学专利公司 2023-07-04 CN disclosed
CN-116209683-A Method for delivering non-aromatic solutions to a polymerization reactor 埃克森美孚化学专利公司 2023-06-02 CN disclosed
CN-113874401-B Metallocenes containing two-SI-SI-bridges 埃克森美孚化学专利公司 2023-04-21 CN disclosed
CN-112334499-B Metallocenes with SI-SI bridge 埃克森美孚化学专利公司 2023-03-24 CN disclosed
CN-111868116-B Ethylene-alpha-olefin-nonconjugated polyene copolymer, process for producing the same, and use thereof 三井化学株式会社 2022-12-09 CN disclosed
CN-114127169-A Propylene polymer composition and molded article 普瑞曼聚合物株式会社 2022-03-01 CN disclosed
CN-110016727-A Ultra-high molecular weight polyethylene powder and ultra high molecular weight polyethylene fiber 旭化成株式会社 2019-07-16 CN disclosed
CN-108976328-B Polyethylene powders and its molding 旭化成株式会社 2019-07-02 CN disclosed
CN-108976328-A Polyethylene powders and its molding 旭化成株式会社 2018-12-11 CN disclosed
CN-108219242-A Polyethylene powders 旭化成株式会社 2018-06-29 CN disclosed
CN-104254546-B The manufacture method of olefin polymer 三井化学株式会社 2016-11-02 CN disclosed