Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28112786 | 0.81 | BIRC5 (0.51) | MAOBTDP2MEN1KMT2A | |
| SCHEMBL28112787 | 0.76 | DYRK1A (0.39) | SMN1; SMN2TDP2S100A4TOP2ATOP2B | |
| SCHEMBL16601684 | 0.70 | USP7 (0.56) | NPC1RAB9ASMN1; SMN2MAOBUSP7 | |
| SCHEMBL28228831 | 0.70 | MEN1 (0.55) | NPC1RAB9ASMN1; SMN2MAOBTDP2 | |
| SCHEMBL12556925 | 0.69 | NPC1 (0.50) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL16656189 | 0.67 | KMT2A (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL15764218 | 0.67 | FYN (0.47) | USP7MAP4K4FYNMINK1TNIK | |
| SCHEMBL16520501 | 0.66 | NPC1 (0.54) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5037032 | 0.65 | CLK1 (0.47) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL12562404 | 0.64 | NPC1 (0.47) | NPC1RAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107068887-B | A kind of organic electroluminescence device and its application | 中节能万润股份有限公司 | 2018-10-02 | — | — | CN | disclosed |
| CN-106188037-B | A kind of compound and its application based on the Fluorenone of 1,8 diaza 9 | 中节能万润股份有限公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-107068887-A | A kind of organic electroluminescence device and its application | 中节能万润股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106188037-A | A kind of compound based on 1,8-diaza-9-Fluorenone and application thereof | 中节能万润股份有限公司 | 2016-12-07 | — | — | CN | disclosed |