Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22066823 | 0.86 | KMT2A (0.41) | DYRK1AAURKADAPK3JAK2PRKD3 | |
| SCHEMBL29407380 | 0.86 | S100A4 (0.44) | DYRK1AAURKADAPK3JAK2PRKD3 | |
| SCHEMBL6347385 | 0.86 | S100A4 (0.44) | DYRK1AAURKADAPK3JAK2PRKD3 | |
| SCHEMBL30029120 | 0.76 | NPSR1 (0.41) | DYRK1AAURKADAPK3JAK2PRKD3 | |
| SCHEMBL20672203 | 0.76 | NPSR1 (0.41) | DYRK1AAURKADAPK3JAK2PRKD3 | |
| SCHEMBL28112338 | 0.76 | NPC1 (0.42) | MAP4K4FYNS100A4KMT2ACDC25B | |
| SCHEMBL29291251 | 0.74 | S100A4 (0.40) | DYRK1AAURKADAPK3JAK2PRKD3 | |
| SCHEMBL4073817 | 0.74 | DYRK1A (0.35) | DYRK1AAURKADAPK3JAK2PRKD3 | |
| SCHEMBL13292088 | 0.73 | TDP2 (0.66) | ABL1S100A4KMT2ACDC25BPTPRC | |
| SCHEMBL22065879 | 0.73 | GAA (0.66) | ABL1S100A4KMT2ACDC25BPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107068887-B | A kind of organic electroluminescence device and its application | 中节能万润股份有限公司 | 2018-10-02 | — | — | CN | disclosed |
| CN-107068887-A | A kind of organic electroluminescence device and its application | 中节能万润股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106188037-A | A kind of compound based on 1,8-diaza-9-Fluorenone and application thereof | 中节能万润股份有限公司 | 2016-12-07 | — | — | CN | disclosed |