Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28112338 | 0.81 | NPC1 (0.42) | MAOBTDP2MEN1KMT2A | |
| SCHEMBL28112787 | 0.72 | DYRK1A (0.39) | TDP2MEN1KMT2A | |
| SCHEMBL29546450 | 0.71 | ALDH1A1 (0.52) | BIRC5MAOBGABRG2GABRB3GABRA5 | |
| SCHEMBL312091 | 0.71 | ALDH1A1 (0.52) | BIRC5MAOBGABRG2GABRB3GABRA5 | |
| SCHEMBL17460460 | 0.70 | GABRG2 (0.55) | BIRC5GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16601738 | 0.70 | MAP4K4 (0.56) | MEN1 | |
| SCHEMBL12441009 | 0.69 | BIRC5 (0.54) | BIRC5GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12556925 | 0.69 | NPC1 (0.50) | MAOBTDP2MEN1KMT2A | |
| SCHEMBL29398919 | 0.69 | ALDH1A1 (0.50) | BIRC5MAOBGABRG2GABRB3GABRA5 | |
| SCHEMBL191276 | 0.69 | ALDH1A1 (0.50) | BIRC5MAOBGABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188037-A | A kind of compound based on 1,8-diaza-9-Fluorenone and application thereof | 中节能万润股份有限公司 | 2016-12-07 | — | — | CN | disclosed |