Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | ADK | P55263 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459854 | 0.88 | KDM4E (0.58) | GSK3BADKSLC22A6NR4A2KDM4E | |
| SCHEMBL27898909 | 0.82 | ALOX5 (0.54) | GSK3BADKKDM4EKMT2AALDH1A1 | |
| SCHEMBL6471859 | 0.81 | GSK3B (0.59) | GSK3BADKSLC22A6NR4A2KDM4E | |
| SCHEMBL8087797 | 0.81 | GSK3B (0.63) | GSK3BADKSLC22A6NR4A2KDM4E | |
| SCHEMBL8087793 | 0.79 | GSK3B (0.57) | GSK3BADKSLC22A6NR4A2KDM4E | |
| SCHEMBL6526599 | 0.78 | GSK3B (0.56) | GSK3BADKSLC22A6NR4A2KDM4E | |
| SCHEMBL27552210 | 0.76 | GSK3B (0.54) | GSK3BADKSLC22A6NR4A2KDM4E | |
| SCHEMBL13689695 | 0.75 | USP2 (0.53) | GSK3BADKSLC22A6NR4A2KDM4E | |
| SCHEMBL30681851 | 0.75 | SLC22A6 (0.53) | GSK3BADKSLC22A6NR4A2KDM4E | |
| SCHEMBL8705925 | 0.75 | SLC22A6 (0.53) | GSK3BADKSLC22A6NR4A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279116-B | A kind of synthesis C2- acetoxy-3-indole ketone compound and method | 南京理工大学 | 2019-04-16 | — | — | CN | claimed |
| CN-106279116-A | A kind of synthesis C2 acetoxyl group 3 indole ketone compound and method | 南京理工大学 | 2017-01-04 | — | — | CN | claimed |
| CN-106279116-B | A kind of synthesis C2- acetoxy-3-indole ketone compound and method | 南京理工大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-106279116-B | A kind of synthesis C2- acetoxy-3-indole ketone compound and method | 南京理工大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-106279116-B | A kind of synthesis C2- acetoxy-3-indole ketone compound and method | 南京理工大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-106279116-A | A kind of synthesis C2 acetoxyl group 3 indole ketone compound and method | 南京理工大学 | 2017-01-04 | — | — | CN | disclosed |