Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | ADK | P55263 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471859 | 0.81 | GSK3B (0.59) | GSK3BADKSLC22A6KMT2AUSP2 | |
| SCHEMBL8087797 | 0.81 | GSK3B (0.63) | GSK3BADKSLC22A6KMT2AUSP2 | |
| SCHEMBL28112445 | 0.79 | GSK3B (0.57) | GSK3BADKSLC22A6KMT2AUSP2 | |
| SCHEMBL6526599 | 0.78 | GSK3B (0.56) | GSK3BADKSLC22A6KMT2AUSP2 | |
| SCHEMBL7459854 | 0.78 | KDM4E (0.58) | GSK3BADKSLC22A6KMT2AHPGD | |
| SCHEMBL27552210 | 0.76 | GSK3B (0.54) | GSK3BADKSLC22A6KMT2AUSP2 | |
| SCHEMBL13689695 | 0.75 | USP2 (0.53) | GSK3BADKSLC22A6KMT2AUSP2 | |
| SCHEMBL27803171 | 0.72 | NR4A2 (0.55) | GSK3BADKSLC22A6KMT2AUSP2 | |
| SCHEMBL11667064 | 0.72 | GSK3B (0.54) | GSK3BADKSLC22A6KMT2AUSP2 | |
| SCHEMBL27898909 | 0.72 | ALOX5 (0.54) | GSK3BADKKMT2AHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555537-B1 | Endothelin antagonists | BANYU PHARMA CO LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |