Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.56 |
| ▸ | EBP | Q15125 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756233 | 0.79 | ESR1 (0.68) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL13109358 | 0.78 | EBP (0.74) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL6756238 | 0.78 | ESR1 (0.80) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL18850172 | 0.78 | ESR1 (0.72) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL6756246 | 0.78 | ESR1 (0.72) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL13350201 | 0.75 | ESR1 (0.71) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL18815845 | 0.75 | EBP (0.55) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL2811903 | 0.74 | EBP (0.88) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL2811811 | 0.74 | EBP (0.86) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL13350303 | 0.74 | EBP (0.86) | ESR1EBPSIGMAR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2192108-B1 | Novel dihydronaphthalene compound and use thereof | UNIV TOKYO SCI EDUC FOUND (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-8183235-B2 | Dihydronaphthalene compound and use thereof | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2012-05-22 | — | — | US | disclosed |
| US-20100249400-A1 | NOVEL DIHYDRONAPHTHALENE COMPOUND AND USE THEREOF | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2192108-A1 | NOVEL DIHYDRONAPHTHALENE COMPOUND AND USE THEREOF | Tokyo University Of Science Educational Foundation Administrative Organization (JP) | 2010-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249400-A1 | NOVEL DIHYDRONAPHTHALENE COMPOUND AND USE THEREOF | PSME1, NDUFB1, NDUFB10 | ESR1 142/4885EBP 1540/4885SIGMAR1 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.