NDUFB1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20
SCHEMBL6267768	0.55	3/20
SCHEMBL1095981	0.55	3/20
SCHEMBL4293165	0.55	3/20
SCHEMBL8490928	0.53	3/20
SCHEMBL8490937	0.53	3/20

Clinical trials — most relevant to NDUFB1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome	PHASE1/PHASE2	COMPLETED
Parkinson's Disease Treatment With Coenzyme Q10	PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Nicotinamide Riboside in Ulcerative Colitis	nan	RECRUITING
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
A RETROspective Study of Patients With TK2d	nan	COMPLETED
Effect of Diaphragm Stimulation During Surgery	nan	COMPLETED
Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy	nan	RECRUITING
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NDUFB1 binder may also engage these)

Protein	Name	Similarity
Q0MQC5	—	1.000	Q0MQC5 →
P0CB74	—	0.998	P0CB74 →
Q02378	—	0.998	Q02378 →
P0DN35	—	0.997	P0DN35 →
P0DN34	—	0.997	P0DN34 →
Q0MQC6	—	0.997	Q0MQC6 →
G2TRP4	—	0.994	G2TRP4 →
P0CB73	—	0.993	P0CB73 →
Q6CLU6	—	0.993	Q6CLU6 →
G2TRM8	—	0.992	G2TRM8 →
P19744	—	0.992	P19744 →
Q6C3K7	—	0.992	Q6C3K7 →
Q67205	—	0.992	Q67205 →
Q8IN43	—	0.992	Q8IN43 →
Q871K1	—	0.991	Q871K1 →
RER1	Protein RER1	0.991	landscape →
MMGT1	ER membrane protein complex subunit 5	0.991	landscape →
Q3J1A3	—	0.991	Q3J1A3 →
Q3E823	—	0.991	Q3E823 →
P30248	—	0.991	P30248 →
G2TRP7	—	0.991	G2TRP7 →
O11982	—	0.991	O11982 →
P04124	—	0.990	P04124 →
Q5BJJ8	—	0.990	Q5BJJ8 →
B2IUK8	—	0.990	B2IUK8 →
P05779	—	0.990	P05779 →
Q77ZL5	—	0.990	Q77ZL5 →
Q77ZK8	—	0.990	Q77ZK8 →
B4PPU4	—	0.990	B4PPU4 →
Q11106	—	0.990	Q11106 →