NDUFB10 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8492838	0.52	4/20
SCHEMBL8492845	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20
SCHEMBL6267768	0.55	3/20
SCHEMBL8493191	0.55	3/20
SCHEMBL1095981	0.55	3/20

Clinical trials — most relevant to NDUFB10 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Effect of Montelukast Versus Co Enzyme in Sepsis	PHASE2/PHASE3	COMPLETED
A Study of Efficacy, Safety and Tolerability of Idebenone in the Treatment of Friedreich's Ataxia (FRDA) Patients	PHASE3	COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
Parkinson's Disease Treatment With Coenzyme Q10	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Ubiquinol (Reduced COQ10) for Patients With Sepsis	PHASE2	COMPLETED
Effects of Coenzyme Q10 on Charcot-Marie-Tooth Disease	PHASE1/PHASE2	COMPLETED
An Open-label Pilot Study of Coenzyme Q10 in Steroid-Treated Duchenne Muscular Dystrophy	PHASE2	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Bioavailability of Ubiquinone and Ubiquinol in Older Adults	PHASE1	COMPLETED
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Q10 Ubiquinol in Autism Spectrum Disorder and in Phelan-McDermid Syndrome.	nan	UNKNOWN
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Concentration of MitoQ in Human Skeletal Muscle	nan	UNKNOWN
Assessment of Follicular Fluid Level of Coenzyme Q10 in Women Undergoing ICSI	nan	UNKNOWN
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis	nan	COMPLETED
Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy	nan	RECRUITING
Fasting Tolerance in MCADD-infants	nan	UNKNOWN
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NDUFB10 binder may also engage these)

Protein	Name	Similarity
P0CC02	—	1.000	P0CC02 →
Q0MQF2	—	1.000	Q0MQF2 →
Q02373	—	1.000	Q02373 →
Q9DCS9	—	0.999	Q9DCS9 →
Q0MQF3	—	0.999	Q0MQF3 →
P0CC01	—	0.998	P0CC01 →
Q1HPL8	—	0.991	Q1HPL8 →
P90789	—	0.980	P90789 →
Q8RWA7	—	0.977	Q8RWA7 →
Q02368	—	0.977	Q02368 →
Q3E7A4	—	0.977	Q3E7A4 →
Q9CR61	—	0.976	Q9CR61 →
A8P488	—	0.976	A8P488 →
B3LG81	—	0.976	B3LG81 →
O49313	—	0.975	O49313 →
Q02772	—	0.975	Q02772 →
Q0UWF1	—	0.975	Q0UWF1 →
Q28GG4	—	0.975	Q28GG4 →
Q6CDV7	—	0.975	Q6CDV7 →
Q17Q91	—	0.974	Q17Q91 →
Q6BY05	—	0.974	Q6BY05 →
Q24276	—	0.974	Q24276 →
Q9ULR0	—	0.974	Q9ULR0 →
Q59QC6	—	0.974	Q59QC6 →
B5X171	—	0.974	B5X171 →
B3MGU5	—	0.973	B3MGU5 →
B6HEJ5	—	0.973	B6HEJ5 →
Q0MQE2	—	0.973	Q0MQE2 →
Q2M2S5	—	0.973	Q2M2S5 →
Q6BVY9	—	0.973	Q6BVY9 →