Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.64 |
| ▸ | EBP | Q15125 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11880808 | 0.94 | ESR1 (0.72) | ESR1ESR2EBPSIGMAR1MIF | |
| SCHEMBL6756238 | 0.89 | ESR1 (0.80) | ESR1ESR2EBPSIGMAR1 | |
| SCHEMBL6756246 | 0.85 | ESR1 (0.72) | ESR1ESR2EBPSIGMAR1 | |
| Hydrochloric Acid SCHEMBL405608 | 0.84 | ESR1 (0.56) | ESR1ESR2EBPSIGMAR1MAPT | |
| SCHEMBL13350201 | 0.82 | ESR1 (0.71) | ESR1ESR2EBPSIGMAR1 | |
| SCHEMBL13109358 | 0.82 | EBP (0.74) | ESR1ESR2EBPSIGMAR1MIF | |
| SCHEMBL18850172 | 0.81 | ESR1 (0.72) | ESR1ESR2EBPSIGMAR1MAPT | |
| SCHEMBL17152127 | 0.79 | ESR1 (0.69) | ESR1ESR2EBPSIGMAR1LTA4H | |
| SCHEMBL2811246 | 0.79 | ESR1 (0.56) | ESR1ESR2EBPSIGMAR1 | |
| SCHEMBL18845488 | 0.79 | EBP (0.58) | ESR1ESR2EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2192108-B1 | Novel dihydronaphthalene compound and use thereof | UNIV TOKYO SCI EDUC FOUND (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-8183235-B2 | Dihydronaphthalene compound and use thereof | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2012-05-22 | — | — | US | disclosed |
| US-8183235-B2 | Dihydronaphthalene compound and use thereof | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2012-05-22 | — | — | US | disclosed |
| US-20100249400-A1 | NOVEL DIHYDRONAPHTHALENE COMPOUND AND USE THEREOF | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100249400-A1 | NOVEL DIHYDRONAPHTHALENE COMPOUND AND USE THEREOF | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2192108-A1 | NOVEL DIHYDRONAPHTHALENE COMPOUND AND USE THEREOF | Tokyo University Of Science Educational Foundation Administrative Organization (JP) | 2010-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249400-A1 | NOVEL DIHYDRONAPHTHALENE COMPOUND AND USE THEREOF | PSME1, NDUFB1, NDUFB10 | ESR1 142/4885ESR2 167/4885EBP 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.