Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11175979 | 0.81 | HSD17B10 (0.56) | TSHRLMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL28112989 | 0.79 | TSHR (0.52) | TSHRLMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7284538 | 0.77 | KMT2A (0.51) | LMNAALDH1A1L3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL28781903 | 0.76 | ALDH1A1 (0.59) | TSHRLMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL873430 | 0.74 | TSHR (1.00) | TSHRALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL22648518 | 0.74 | MEN1 (0.59) | TSHRLMNAALDH1A1MAPTNPC1 | |
| SCHEMBL13049037 | 0.74 | MEN1 (0.59) | TSHRLMNAALDH1A1MAPTNPC1 | |
| SCHEMBL12027622 | 0.74 | MEN1 (0.59) | TSHRLMNAALDH1A1MAPTNPC1 | |
| SCHEMBL6689255 | 0.74 | ALDH1A1 (0.44) | TSHRLMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5843161 | 0.73 | LMNA (0.46) | TSHRLMNAALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011043-B | The quinuclidine esters of 1-aza heterocycles guanidine-acetic acid, their preparation method and Pharmaceutical composition thereof as muscarine antagonist | 奇斯药制品公司 | 2016-11-16 | — | — | CN | disclosed |