Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5843120 | 0.98 | ALDH1A1 (0.45) | LMNAALDH1A1RAB9AMAPTHPGD | |
| SCHEMBL15844822 | 0.87 | LMNA (0.57) | LMNAALDH1A1RAB9AMAPTKMT2A | |
| SCHEMBL12246311 | 0.79 | ALDH1A1 (0.42) | LMNAALDH1A1RAB9AMAPTHPGD | |
| SCHEMBL6836087 | 0.78 | L3MBTL1 (0.56) | ALDH1A1RAB9AKMT2ANPSR1TSHR | |
| SCHEMBL21026773 | 0.76 | ALDH1A1 (0.40) | LMNAALDH1A1RAB9AMAPTHPGD | |
| SCHEMBL15174342 | 0.76 | KMT2A (0.41) | LMNAALDH1A1RAB9AMAPTHPGD | |
| SCHEMBL15174290 | 0.76 | HCAR2 (0.45) | LMNAALDH1A1RAB9AMAPTHPGD | |
| SCHEMBL15174291 | 0.76 | HCAR2 (0.45) | LMNAALDH1A1RAB9AMAPTHPGD | |
| SCHEMBL7382077 | 0.75 | ALDH1A1 (0.37) | LMNAALDH1A1RAB9AMAPTHPGD | |
| SCHEMBL465226 | 0.74 | LMNA (0.45) | LMNAALDH1A1RAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034020-B2 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCE (US) | 2006-04-25 | — | — | US | disclosed |
| US-20040127564-A1 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES | 2004-07-01 | — | — | US | disclosed |
| US-6664394-B2 | As inactivator of antigen- specific T cells is useful in the prophylaxis or therapy of autoimmune diseases, disorders involving an autoimmune component or neoplastic diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2003-12-16 | — | — | US | disclosed |
| US-20020143056-A1 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES | 2002-10-03 | — | — | US | disclosed |
| US-6407107-B1 | 4-(MORPHOLINO)ALKYL BUTANAMIDE DERIVATIVES; AUTOIMMUNE DISEASES; ANTICARCINOGENIC AGENTS | THE BOARD OF TRUSTEES OF THE UNVERSITY OF ARKANSAS | 2002-06-18 | — | — | US | disclosed |
| WO-2000073257-A1 | DERIVATIVES OF BUTYRIC ACID AND USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143056-A1 | Derivatives of butyric acid and uses thereof | CD4, NFATC1, GABRA4 | LMNA 2350/4885ALDH1A1 858/4885RAB9A 4163/4885 |
| US-20040127564-A1 | Derivatives of butyric acid and uses thereof | CD4, NFATC1, GABRA4 | LMNA 2318/4885ALDH1A1 849/4885RAB9A 4109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.