Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15563887 | 0.75 | DAO (0.49) | HPGDALDH1A1SMN1; SMN2PKMDAO | |
| SCHEMBL28113645 | 0.75 | HTR2C (0.43) | HPGDALDH1A1CYP3A4SMN1; SMN2PKM | |
| SCHEMBL7656600 | 0.73 | ALDH1A1 (0.49) | ALDH1A1CYP3A4SMN1; SMN2DAOPOLB | |
| SCHEMBL10330274 | 0.73 | PTGER1 (0.49) | POLBKDM4EMEN1KMT2A | |
| SCHEMBL15563837 | 0.72 | GRIA1 (0.49) | HPGDALDH1A1CYP3A4SMN1; SMN2PKM | |
| SCHEMBL7833852 | 0.72 | HPGD (0.53) | HPGDALDH1A1DAOPOLBKDM4E | |
| SCHEMBL28113599 | 0.72 | HPGD (0.41) | HPGDALDH1A1CYP3A4SMN1; SMN2PKM | |
| SCHEMBL30928935 | 0.71 | ALDH1A1 (0.57) | HPGDALDH1A1CYP3A4SMN1; SMN2PKM | |
| SCHEMBL17610952 | 0.71 | HTR2A (0.42) | CYP3A4SMN1; SMN2KDM4EHTR2CMALT1 | |
| SCHEMBL15075338 | 0.70 | SMN1; SMN2 (0.38) | HPGDSMN1; SMN2POLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106304835-A | Sgc stimulant | 铁木医药有限公司 | 2017-01-04 | — | — | CN | disclosed |