Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | AGER | Q15109 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714175 | 0.80 | MAPK1 (0.73) | RAB9ANPC1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL12443375 | 0.78 | RAB9A (1.00) | RAB9ANPC1KCNMA1TSHRAGER | |
| SCHEMBL419203 | 0.76 | MAPK1 (0.76) | RAB9ANPC1KCNMA1TSHRSMN1; SMN2 | |
| SCHEMBL16607160 | 0.76 | AGER (1.00) | RAB9ANPC1KCNMA1TSHRAGER | |
| SCHEMBL24934051 | 0.76 | RAB9A (0.72) | RAB9ANPC1KCNMA1TSHRAGER | |
| SCHEMBL16073069 | 0.76 | RAB9A (0.72) | RAB9ANPC1KCNMA1TSHRAGER | |
| SCHEMBL4288699 | 0.76 | AGER (0.72) | RAB9ANPC1KCNMA1TSHRAGER | |
| Bromide SCHEMBL27908055 | 0.75 | MAPK1 (0.74) | RAB9ANPC1KCNMA1TSHRSMN1; SMN2 | |
| SCHEMBL18825301 | 0.75 | RAB9A (0.71) | RAB9ANPC1KCNMA1TSHRAGER | |
| SCHEMBL4286251 | 0.75 | RAB9A (0.71) | RAB9ANPC1KCNMA1TSHRAGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106316979-B | A kind of preparation method of acotiamide hydrochloride hydrate | 山东罗欣药业集团股份有限公司 | 2018-11-27 | — | — | CN | claimed |
| CN-106316979-A | Acotiamide hydrochloride preparation method | 山东罗欣药业集团股份有限公司 | 2017-01-11 | — | — | CN | claimed |
| CN-106316979-B | A kind of preparation method of acotiamide hydrochloride hydrate | 山东罗欣药业集团股份有限公司 | 2018-11-27 | — | — | CN | disclosed |
| CN-106316979-A | Acotiamide hydrochloride preparation method | 山东罗欣药业集团股份有限公司 | 2017-01-11 | — | — | CN | disclosed |