Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704679 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL18334347 | 0.82 | BLM (0.42) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL15948817 | 0.81 | CES2 (0.48) | ODC1KMT2AMEN1CES2 | |
| Trifluoroacetic Acid SCHEMBL10619767 | 0.76 | ODC1 (0.48) | ODC1LMNABLMKDM4EMAPT | |
| Trifluoroacetic Acid SCHEMBL6490887 | 0.76 | HRH4 (0.50) | ODC1LMNABLMKDM4EMAPT | |
| Trifluoroacetic Acid SCHEMBL3149196 | 0.76 | ODC1 (0.48) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL25371748 | 0.75 | LMNA (0.48) | LMNABLMPMP22THRBKMT2A | |
| SCHEMBL10633321 | 0.75 | CES2 (0.34) | ODC1TSHRCES2 | |
| SCHEMBL1706449 | 0.75 | CES2 (0.54) | KMT2ACYP1A2MEN1CES2 | |
| SCHEMBL4812451 | 0.75 | ODC1 (0.53) | ODC1LMNABLMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132922-A | One class water solublity propofol derivative and application thereof | 江苏恩华络康药物研发有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-106132922-A | One class water solublity propofol derivative and application thereof | 江苏恩华络康药物研发有限公司 | 2016-11-16 | — | — | CN | disclosed |