Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.46 |
| ▸ | ICMT | O60725 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787118 | 0.85 | AKR1C2 (0.70) | AKR1C2AKR1C1DHODHLMNAERCC5 | |
| SCHEMBL787129 | 0.81 | AKR1C2 (0.54) | AKR1C2AKR1C1CNR1NPC1LMNA | |
| SCHEMBL1786128 | 0.81 | LMNA (0.50) | PARP1NPC1LMNARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28752341 | 0.79 | LMNA (0.49) | PARP1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6667275 | 0.77 | BCAT2 (0.65) | DHODHTLR8PARP1CDC7NPC1 | |
| SCHEMBL12394209 | 0.76 | DHODH (0.64) | DHODHPARP1MKNK1MKNK2CSF1R | |
| SCHEMBL6508314 | 0.75 | AKR1C2 (0.70) | AKR1C2AKR1C1DHODHCNR1SMN1; SMN2 | |
| SCHEMBL8365173 | 0.75 | AHR (0.61) | AKR1C2AKR1C1CNR1RAB9A | |
| SCHEMBL29723862 | 0.75 | PARP1 (0.52) | AKR1C2AKR1C1DHODHTLR8PARP1 | |
| SCHEMBL5605353 | 0.74 | PARP1 (0.78) | DHODHTLR8PARP1ICMTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106166157-A | Sulfonamides heterocyclic carbamate derivatives as anti-hepatitis b virus infected antiviral agent | 巴鲁·S·布隆伯格研究所 | 2016-11-30 | — | — | CN | claimed |