Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981527 | 0.88 | HSD11B1 (0.52) | HSD11B1ALDH1A1POLBSRD5A2CYP3A4 | |
| SCHEMBL1759305 | 0.84 | TTR (0.56) | HSD11B1ALDH1A1POLBSRD5A2CYP3A4 | |
| SCHEMBL10467015 | 0.83 | PRKCI (0.43) | HSD11B1ALDH1A1POLBCYP3A4GAA | |
| SCHEMBL2813230 | 0.80 | TTR (0.50) | ALDH1A1POLBSRD5A2CYP3A4GAA | |
| SCHEMBL31473460 | 0.78 | KDM4E (0.51) | ALDH1A1POLBGAAMAPTMAPK1 | |
| SCHEMBL1759210 | 0.78 | KDM4E (0.51) | ALDH1A1POLBGAAMAPTMAPK1 | |
| SCHEMBL10609508 | 0.77 | SRD5A2 (0.55) | ALDH1A1POLBSRD5A2MAPTMAPK1 | |
| SCHEMBL27620600 | 0.77 | ALDH1A1 (0.56) | HSD11B1ALDH1A1POLBSRD5A2GAA | |
| SCHEMBL2812669 | 0.73 | TDP1 (0.47) | ALDH1A1POLBCYP3A4GAAMAPT | |
| SCHEMBL437529 | 0.73 | ALDH1A1 (0.66) | ALDH1A1POLBSRD5A2CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | HSD11B1 450/4885ALDH1A1 401/4885POLB 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.