Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655600 | 0.83 | HPGD (0.55) | KMT2ALMNAMAPTKDM4EHTT | |
| SCHEMBL13655548 | 0.83 | MEN1 (0.45) | KMT2AHTTTSHR | |
| SCHEMBL10889755 | 0.81 | KMT2A (0.69) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL13655565 | 0.77 | NPC1 (0.56) | KMT2ALMNA | |
| SCHEMBL9695573 | 0.76 | HTT (0.63) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL5849754 | 0.76 | HTT (0.63) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL7150327 | 0.75 | KMT2A (0.61) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL30508514 | 0.75 | KMT2A (0.61) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL30525000 | 0.75 | KMT2A (0.61) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL10158103 | 0.75 | HTT (0.68) | KMT2AAPEX1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478718-B | Application without copper catalysis click chemistry module molecule and its in a medicament | 中国药科大学 | 2018-07-31 | — | — | CN | disclosed |
| CN-106478718-A | No copper catalysis click chemistry module molecule and its application in a medicament | 中国药科大学 | 2017-03-08 | — | — | CN | disclosed |