Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113685 | 0.83 | KMT2A (0.53) | KMT2AHTTTSHR | |
| SCHEMBL13655600 | 0.82 | HPGD (0.55) | MEN1KMT2AHTTTSHRNPC1 | |
| SCHEMBL772204 | 0.77 | ALDH1A1 (0.54) | MEN1KMT2ATDP1HTTTSHR | |
| SCHEMBL13667371 | 0.76 | MEN1 (0.51) | MEN1KMT2ATDP1HTTTSHR | |
| SCHEMBL13655570 | 0.74 | KDM4E (0.52) | MEN1KMT2A | |
| SCHEMBL28016258 | 0.73 | TSHR (0.77) | HTTTSHRDRD2DRD3HCRTR1 | |
| SCHEMBL8598789 | 0.73 | NPC1 (0.67) | HTTTSHRNPC1RAB9AHPGD | |
| SCHEMBL13655565 | 0.73 | NPC1 (0.56) | MEN1KMT2ADRD2DRD3NPC1 | |
| SCHEMBL4352870 | 0.72 | KMT2A (0.55) | MEN1KMT2ATDP1HTTTSHR | |
| SCHEMBL11330575 | 0.71 | NAAA (0.70) | HTTTSHRHCRTR1HPGDALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9351491-B2 | Inhibition and dispersion of biofilms in plants with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-05-31 | — | — | US | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-20130315874-A1 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-11-28 | — | — | US | disclosed |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2013-05-23 | — | — | US | disclosed |
| US-8367713-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367713-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-02-05 | — | — | US | disclosed |
| US-20110117158-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-05-19 | — | — | US | disclosed |
| US-20110117158-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-05-19 | — | — | US | disclosed |
| US-7897631-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897631-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897631-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-01 | — | — | US | disclosed |
| WO-2010077603-A1 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2009131654-A2 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | MEN1 3635/4885KMT2A 2654/4885TDP1 517/4885 |
| US-20110117158-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | MEN1 3635/4885KMT2A 2654/4885TDP1 517/4885 |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | MEN1 3635/4885KMT2A 2654/4885TDP1 517/4885 |
| US-20130315874-A1 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | SOD1, APOBEC3A, CLPP | MEN1 3530/4885KMT2A 2208/4885TDP1 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.