SCHEMBL28113843

SCHEMBL28113843

Brc1cc(Br)cc(Br)c1.N=C=O.O=C=Nc1c(F)cc(Br)cc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL446044 0.92 GABRA1 (0.33)
SCHEMBL1457283 0.82 GABRA1 (0.31)
SCHEMBL160448 0.74 GABRA1 (0.35)
SCHEMBL6964625 0.71 GABRA1 (0.38)
SCHEMBL30438624 0.71 MAPT (0.32)
SCHEMBL1020714 0.71 MAPT (0.32)
SCHEMBL2728021 0.70 TDP1 (0.36)
SCHEMBL8917308 0.69 CYP3A4 (0.43)
SCHEMBL940455 0.69 GABRA1 (0.32)
SCHEMBL28560711 0.68 VCAM1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232666-A Post-modification polycarbodiimide 巴斯夫欧洲公司 2016-12-14 CN disclosed