SCHEMBL160448

SCHEMBL160448

O=C=Nc1c(F)cc(F)cc1F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
ERN1 O75460 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30438624 0.85 MAPT (0.32) GABRA1GABRB2
SCHEMBL1020714 0.85 MAPT (0.32) GABRA1GABRB2
SCHEMBL28557793 0.85 CYP3A4 (0.36) GABRA1GABRB2
SCHEMBL1952585 0.85 MAPK1 (0.38) GABRA1GABRB2MAPK1TDP1
SCHEMBL10614700 0.82 GABRA1 (0.48) GABRA1GABRB2
SCHEMBL446044 0.81 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL6964625 0.81 GABRA1 (0.38) GABRA1GABRB2MAPK1TDP1
SCHEMBL940455 0.79 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL8917308 0.79 CYP3A4 (0.43) GABRA1GABRB2
SCHEMBL28560711 0.78 VCAM1 (0.32) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025102678-A1 ELECTROLYTE ADDITIVE COMPOSITION, ELECTROLYTE, BATTERY, AND ELECTRIC DEVICE 宁德时代新能源科技股份有限公司 2025-05-22 WO claimed
CN-120021059-A Electrolyte additive composition, electrolyte, battery and electric device 宁德时代新能源科技股份有限公司 2025-05-20 CN claimed
CN-119742416-A Secondary battery and electronic device 宁德新能源科技有限公司 2025-04-01 CN claimed
CN-118899513-B Secondary battery and electronic device 宁德新能源科技有限公司 2025-01-28 CN claimed
CN-118899513-A Secondary battery and electronic device 宁德新能源科技有限公司 2024-11-05 CN claimed
CN-117285890-A Preparation method of formaldehyde-free environment-friendly flame-retardant plywood 南宁市匠心鸣居建筑材料有限公司 2023-12-26 CN claimed
CN-112724785-B High-environmental-protection water-based waterproof coating 安徽酉阳防水科技有限公司 2021-10-01 CN claimed
CN-112724785-A High-environmental-protection water-based waterproof coating 安徽酉阳防水科技有限公司 2021-04-30 CN claimed
US-20250223263-A1 SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME NodThera Limited (GB) 2025-07-10 US disclosed
WO-2025102678-A1 ELECTROLYTE ADDITIVE COMPOSITION, ELECTROLYTE, BATTERY, AND ELECTRIC DEVICE 宁德时代新能源科技股份有限公司 2025-05-22 WO disclosed
CN-120021059-A Electrolyte additive composition, electrolyte, battery and electric device 宁德时代新能源科技股份有限公司 2025-05-20 CN disclosed
CN-119742416-A Secondary battery and electronic device 宁德新能源科技有限公司 2025-04-01 CN disclosed
US-12247011-B2 Selective inhibitors of NLRP3 inflammasome NodThera Limited (GB) 2025-03-11 US disclosed
CN-118899513-B Secondary battery and electronic device 宁德新能源科技有限公司 2025-01-28 CN disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed
CN-86108416-A Oxazolidinedione derivative, process for producing the same, and herbicide containing the same 1987-07-29 CN disclosed
US-4477389-A Polyhalogenated phenyl isocyanate synthesis with excess phosgene and either triethylamine or tetramethylurea THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1984-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12247011-B2 Selective inhibitors of NLRP3 inflammasome NLRP3, NOD1, NLRP1 GABRA1 2922/4885GABRB2 2882/4885CES2 4796/4885
US-20250223263-A1 SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME NLRP3, NOD1, NLRP1 GABRA1 2922/4885GABRB2 2882/4885CES2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.