SCHEMBL28113872

SCHEMBL28113872

C=CC(=O)NS(=O)(=O)OCC(C)C.[CH2]C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1670876 0.95 TSHR (0.44) TSHRALDH1A1MAPK1TDP1
Ammonia Solution, Strong SCHEMBL28169208 0.93 TSHR (0.43) TSHRALDH1A1MAPK1TDP1
SCHEMBL28137277 0.93 TSHR (0.43) TSHRALDH1A1MAPK1TDP1
SCHEMBL27747237 0.75 TSHR (0.37) TSHRALDH1A1MAPK1TDP1
SCHEMBL15668728 0.73 TSHR (0.38) TSHRALDH1A1MAPK1TDP1
SCHEMBL13773169 0.73 TSHR (0.36) TSHRALDH1A1TDP1
SCHEMBL28575047 0.73 ALDH1A1 (0.34) TSHRALDH1A1MAPK1TDP1
SCHEMBL27998242 0.73 TSHR (0.46) TSHRALDH1A1
SCHEMBL6687517 0.73 ZDHHC20 (0.38) TSHRALDH1A1MAPK1TDP1
SCHEMBL27676449 0.72 TSHR (0.43) TSHRALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232093-B The method for inhibiting copper to deposit on hair 宝洁公司 2019-09-20 CN disclosed
CN-109414599-A Hair care composition comprising metathesized unsaturated polyol ester 宝洁公司 2019-03-01 CN disclosed
CN-109310589-A Hair care composition for calcium chelating 宝洁公司 2019-02-05 CN disclosed
CN-109090809-A For applying the application device component of composition 宝洁公司 2018-12-28 CN disclosed
CN-108697909-A Method of cleansing hair using low pH hair care compositions 宝洁公司 2018-10-23 CN disclosed
CN-105050567-B Include the personal care composition of pre-emulsified preparation 宝洁公司 2018-04-27 CN disclosed
CN-107106456-A Method for improving volume and combability using personal care compositions comprising pre-emulsified formulations 宝洁公司 2017-08-29 CN disclosed
CN-106232095-A Method for inhibiting copper deposition on hair 宝洁公司 2016-12-14 CN disclosed
CN-106232093-A The method that suppression copper deposits on hair 宝洁公司 2016-12-14 CN disclosed
CN-106232094-A Method for inhibiting copper deposition on hair 宝洁公司 2016-12-14 CN disclosed
CN-106232096-A Comprise the shampoo Compositions of gel-type vehicle and histidine 宝洁公司 2016-12-14 CN disclosed