Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14780140 | 0.77 | KMT2A (0.49) | PAX8KMT2AMEN1RAB9AMAPT | |
| SCHEMBL31260000 | 0.77 | KMT2A (0.49) | PAX8KMT2AMEN1RAB9AMAPT | |
| SCHEMBL5738819 | 0.77 | KMT2A (0.62) | PAX8KMT2AMEN1RAB9AMAPT | |
| SCHEMBL1736342 | 0.76 | NPC1 (0.52) | PAX8KMT2AMEN1RAB9AHSD11B1 | |
| SCHEMBL18497234 | 0.75 | PAX8 (1.00) | PAX8KMT2AMEN1RAB9AHSD11B1 | |
| SCHEMBL6309320 | 0.75 | TXNRD1 (0.65) | PAX8RAB9AMAPTHTT | |
| Hydrochloric Acid SCHEMBL18497226 | 0.74 | PAX8 (0.97) | PAX8KMT2AMEN1RAB9AHSD11B1 | |
| SCHEMBL30425516 | 0.74 | PDE10A (0.51) | PAX8KMT2AMEN1RAB9AMAPT | |
| SCHEMBL9986678 | 0.74 | PDE10A (0.51) | PAX8KMT2AMEN1RAB9AMAPT | |
| SCHEMBL8566533 | 0.72 | ALDH1A1 (0.53) | PAX8KMT2AMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103814021-B | Dihydroquinoline 2 ketone derivatives | 霍夫曼-拉罗奇有限公司 | 2016-12-21 | — | — | CN | disclosed |