Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23362197 | 0.82 | LMNA (0.48) | LMNAKDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL29640631 | 0.82 | LMNA (0.48) | LMNAKDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL7578838 | 0.80 | KDM4E (0.59) | LMNAKDM4EMEN1KMT2APIK3CD | |
| SCHEMBL29576694 | 0.80 | KDM4E (0.59) | LMNAKDM4EMEN1KMT2APIK3CD | |
| SCHEMBL29744413 | 0.78 | MYC (0.38) | LMNAKDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL23497662 | 0.78 | MYC (0.38) | LMNAKDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL7121601 | 0.77 | KDM4E (0.69) | LMNAKDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL2070531 | 0.75 | LMNA (0.71) | LMNA | |
| SCHEMBL10474320 | 0.75 | LMNA (0.55) | LMNAKDM4EMEN1KMT2ACAPN1 | |
| SCHEMBL18589519 | 0.73 | LMNA (0.54) | LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132422-A | Adoptive cell therapy using agonists of retinoic acid receptor-associated orphan receptor gamma & related therapeutic methods | 莱斯拉公司 | 2016-11-16 | — | — | CN | disclosed |