SCHEMBL28114489

SCHEMBL28114489

Fc1ccc(-c2ccc[nH]2)c(F)c1.[Ir]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 8/20 0.42
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
HPGD P15428 2/20 0.38
KMT2A Q03164 2/20 0.38
THRB P10828 1/20 0.38
PDGFRB P09619 1/20 0.38
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
DHFR P00374 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
LMNA P02545 1/20 0.36
TTR P02766 1/20 0.36
ALB P02768 1/20 0.36
HMGB1 P09429 1/20 0.36
CXCL12 P48061 1/20 0.36
HIF1A Q16665 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
ACMSD Q8TDX5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27801911 0.98 CDK2 (0.43) CDK2ALDH1A1MEN1HPGDKMT2A
Pyridine SCHEMBL28089565 0.87 CYP3A4 (0.40) CDK2ALDH1A1MEN1HPGDKMT2A
Piperidine SCHEMBL28335205 0.85 CDK2 (0.36) CDK2ALDH1A1MEN1HPGDKMT2A
SCHEMBL17376563 0.82 CDK2 (0.43) CDK2
SCHEMBL15416935 0.77 CDK2 (0.44) CDK2
SCHEMBL28129725 0.76 HSD11B1 (0.37) CDK2MEN1KMT2APDGFRBAHR
SCHEMBL28311619 0.76 IDO1 (0.57) CDK2ALDH1A1MEN1HPGDKMT2A
SCHEMBL24696655 0.75 CDK2 (0.42) CDK2ALDH1A1MEN1KMT2A
SCHEMBL16880624 0.75 ALDH1A1 (0.41) CDK2ALDH1A1
SCHEMBL4864306 0.75 MAPKAPK2 (0.41) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101899037-B The derivant with hetero-aromatic ring, the light-emitting component using it, light-emitting device, illuminator and electronic equipment 株式会社半导体能源研究所 2016-12-21 CN disclosed