Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28105602 | 0.80 | KMO (0.50) | KMOTGFBR1MEN1NPC1RAB9A | |
| SCHEMBL27801911 | 0.77 | CDK2 (0.43) | MEN1KMT2A | |
| SCHEMBL3446347 | 0.76 | ITK (0.47) | MAPKAPK2KDRPLK4MAPK13DAPK3 | |
| SCHEMBL28114489 | 0.75 | CDK2 (0.42) | MEN1KMT2A | |
| SCHEMBL16242291 | 0.75 | KMO (0.47) | KMOKDM4CTGFBR1MEN1NPC1 | |
| SCHEMBL19072696 | 0.75 | KMO (0.54) | MAPK13MAPK12MAPK14KMOKDM4C | |
| SCHEMBL29445848 | 0.75 | KMO (0.54) | MAPK13MAPK12MAPK14KMOKDM4C | |
| SCHEMBL3446349 | 0.74 | NR4A2 (0.54) | MAP4K4PIM1MAPK1DYRK1ACLK4 | |
| SCHEMBL23417018 | 0.74 | IDO1 (0.49) | KDRMAPK13MAP4K4MAPK1MAPK12 | |
| Pyridine SCHEMBL28089565 | 0.74 | CYP3A4 (0.40) | MAPK14KMOKDM4CTGFBR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320835-B2 | Phosphorescent material | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-22 | — | — | US | disclosed |
| US-20050196637-A1 | Phosphorescent material | LG CHEM, LTD. (KR) | 2005-09-08 | — | — | US | disclosed |