Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633498 | 0.98 | FAAH (0.55) | TSHRHSD17B10FAAHPOLBALDH1A1 | |
| SCHEMBL26393724 | 0.98 | FAAH (0.55) | TSHRHSD17B10FAAHPOLBALDH1A1 | |
| SCHEMBL1726735 | 0.95 | TSHR (0.57) | TSHRHSD17B10POLBALDH1A1TDP1 | |
| SCHEMBL21999365 | 0.91 | ALDH1A1 (0.60) | HSD17B10FAAHALDH1A1KDM4EMEN1 | |
| SCHEMBL21999366 | 0.91 | ALDH1A1 (0.60) | HSD17B10FAAHALDH1A1KDM4EMEN1 | |
| SCHEMBL9544143 | 0.91 | ALDH1A1 (0.60) | HSD17B10FAAHALDH1A1KDM4EMEN1 | |
| SCHEMBL9633172 | 0.91 | ALDH1A1 (0.60) | HSD17B10FAAHALDH1A1KDM4EMEN1 | |
| SCHEMBL21998731 | 0.91 | ALDH1A1 (0.60) | HSD17B10FAAHALDH1A1KDM4EMEN1 | |
| SCHEMBL8591441 | 0.91 | ALDH1A1 (0.60) | HSD17B10FAAHALDH1A1KDM4EMEN1 | |
| SCHEMBL7747987 | 0.91 | TLR2 (0.52) | TSHRHSD17B10FAAHPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108383804-A | The crystal form of neurotrophin simulated compound and its salt | 特罗菲克斯制药股份有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-104761515-B | The crystal formation of neurotrophin simulated compound and its salt | 特罗菲克斯制药股份有限公司 | 2018-03-09 | — | — | CN | disclosed |
| WO-2017176040-A1 | HETEROCYCLIC COMPOUND DECOMPOSING RAS AND USES THEREOF | 연세대학교 산학협력단 | 2017-10-12 | — | — | WO | disclosed |
| WO-2010102212-A2 | NEUROTROPHIN MIMETICS AND USES THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2010-09-10 | — | — | WO | disclosed |