Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28313659 | 0.84 | OPRL1 (0.42) | MEN1KMT2AALDH1A1OPRM1 | |
| SCHEMBL1220833 | 0.83 | GAA (0.48) | MEN1KMT2ALMNAGAAPOLB | |
| Hydrochloric Acid SCHEMBL28686967 | 0.82 | GAA (0.47) | MEN1KMT2ALMNAGAAPOLB | |
| Tert-Butyl Formate SCHEMBL28314943 | 0.82 | MAOA (0.50) | MEN1KMT2AALDH1A1OPRM1 | |
| Tert-Butyl Formate SCHEMBL27748185 | 0.79 | TACR1 (0.45) | OPRM1 | |
| Tert-Butyl Formate SCHEMBL28801033 | 0.78 | TDP1 (0.39) | — | |
| Tert-Butyl Formate SCHEMBL27822580 | 0.76 | TDP1 (0.43) | — | |
| Tert-Butyl Formate SCHEMBL28821595 | 0.76 | OPRL1 (0.38) | OPRM1 | |
| Tert-Butyl Formate SCHEMBL28114837 | 0.75 | TDP1 (0.36) | — | |
| Tert-Butyl Formate SCHEMBL27567173 | 0.74 | DRD2 (0.45) | ALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164066-A | Cyclopropylamines as lsd1 inhibitors | 因赛特公司 | 2016-11-23 | — | — | CN | disclosed |