Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27297887 | 0.83 | L3MBTL1 (0.36) | L3MBTL1TDP1LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL28329349 | 0.80 | — | — | |
| SCHEMBL22912582 | 0.76 | L3MBTL1 (0.41) | L3MBTL1TDP1LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL28083974 | 0.73 | — | — | |
| SCHEMBL16232245 | 0.73 | NOTUM (0.44) | TDP1TSHRMAPK1ALDH1A1POLB | |
| SCHEMBL6490655 | 0.72 | L3MBTL1 (0.40) | L3MBTL1TDP1LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL97309 | 0.71 | ERN1 (0.36) | TDP1LMNATSHRALDH1A1CYP1A2 | |
| SCHEMBL10926498 | 0.70 | LMNA (0.31) | LMNASMN1; SMN2CYP2C9TSHRAPEX1 | |
| SCHEMBL7995407 | 0.70 | LMNA (0.41) | L3MBTL1TDP1LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL28089027 | 0.69 | GRM2 (0.37) | L3MBTL1SMN1; SMN2TSHRALDH1A1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232582-A | Aryl and heteroaryl ether compound as ROR gamma modulators | 格兰马克药品股份有限公司 | 2016-12-14 | — | — | CN | disclosed |