Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | WHR1 | P49842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115284 | 0.85 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KDM4EPDGFRBPDGFRA | |
| SCHEMBL28114790 | 0.85 | PDGFRB (0.65) | ALDH1A1SMN1; SMN2KDM4EPDGFRBPDGFRA | |
| SCHEMBL29392356 | 0.80 | CLK4 (0.51) | ALDH1A1SMN1; SMN2KDM4EPDGFRBPDGFRA | |
| SCHEMBL28850273 | 0.80 | CLK4 (0.51) | ALDH1A1SMN1; SMN2KDM4EPDGFRBPDGFRA | |
| SCHEMBL3873292 | 0.74 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4EPDGFRBPDGFRA | |
| SCHEMBL1516947 | 0.74 | FYN (0.44) | FYNNPC1RAB9AKMT2ARET | |
| SCHEMBL4250021 | 0.73 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KDM4EPDGFRBPDGFRA | |
| SCHEMBL14320513 | 0.72 | CLK4 (0.46) | ALDH1A1SMN1; SMN2KDM4EMAPTFYN | |
| SCHEMBL2148656 | 0.71 | TRPM8 (0.74) | — | |
| SCHEMBL21537534 | 0.70 | MAP4K4 (0.59) | ALDH1A1SMN1; SMN2KDM4EMAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083740-B | The 4- anilinoquinazoline derivatives and preparation method of a kind of triazole containing 1,2,3- | 江苏开放大学 | 2018-05-15 | — | — | CN | disclosed |
| CN-106083740-A | A kind of 4 anilinoquinazoline derivatives containing 1,2,3 triazoles and preparation method | 江苏开放大学 | 2016-11-09 | — | — | CN | disclosed |