Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 8/20 | 0.65 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | WHR1 | P49842 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | STAT6 | P42226 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114789 | 0.85 | ALDH1A1 (0.49) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28115284 | 0.84 | ALDH1A1 (0.51) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28850273 | 0.82 | CLK4 (0.51) | PDGFRBPDGFRAALDH1A1SMN1; SMN2GLA | |
| SCHEMBL29392356 | 0.82 | CLK4 (0.51) | PDGFRBPDGFRAALDH1A1SMN1; SMN2GLA | |
| SCHEMBL17348541 | 0.81 | GAA (0.47) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31325764 | 0.79 | NPC1 (0.59) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29928263 | 0.79 | NPC1 (0.59) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3873292 | 0.79 | ALDH1A1 (0.49) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL595944 | 0.79 | SMN1; SMN2 (1.00) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29351353 | 0.79 | SMN1; SMN2 (1.00) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083740-A | A kind of 4 anilinoquinazoline derivatives containing 1,2,3 triazoles and preparation method | 江苏开放大学 | 2016-11-09 | — | — | CN | disclosed |