Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAOA | P21397 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31325764 | 0.88 | NPC1 (0.59) | NPC1RAB9AEGFRKMT2AMEN1 | |
| SCHEMBL9938089 | 0.84 | KDM4E (0.55) | NPC1RAB9AMAOAMAOBEGFR | |
| SCHEMBL8779400 | 0.82 | NPC1 (0.50) | NPC1RAB9AMAOAMAOBEGFR | |
| SCHEMBL16404354 | 0.81 | CYP1A2 (0.62) | NPC1RAB9AMAOAMAOBKMT2A | |
| SCHEMBL28110409 | 0.80 | CYP1A2 (0.59) | RAB9AKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL31023430 | 0.80 | CYP1A2 (0.59) | RAB9AKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL29377866 | 0.79 | PDGFRB (0.75) | NPC1RAB9AEGFRKMT2AMEN1 | |
| SCHEMBL28114790 | 0.79 | PDGFRB (0.65) | KMT2AMEN1ALDH1A1MAPTPDGFRB | |
| SCHEMBL17691569 | 0.79 | MAOA (0.58) | NPC1RAB9AMAOAMAOBALDH1A1 | |
| SCHEMBL14314827 | 0.78 | MAOA (0.53) | NPC1RAB9AMAOAMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528823-A | Synthesis method of 2-aryl quinazoline compound | 武汉科技大学 | 2025-02-28 | — | — | CN | disclosed |
| CN-113200926-B | Method for modifying 2-aryl quinazoline-4 (3H) -ketone compound | 四川大学 | 2022-09-23 | — | — | CN | disclosed |