Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508386 | 0.87 | ATM (0.51) | KMT2AMEN1HPGDNPSR1L3MBTL1 | |
| SCHEMBL955421 | 0.85 | ATM (0.42) | KMT2AMEN1HPGDNPSR1L3MBTL1 | |
| SCHEMBL621197 | 0.81 | TDP1 (0.52) | KMT2AMEN1L3MBTL1ATMTDP1 | |
| SCHEMBL135219 | 0.81 | ALDH1A1 (0.53) | KMT2AMEN1HPGDNPSR1L3MBTL1 | |
| SCHEMBL28114927 | 0.81 | HPGD (0.52) | KMT2AMEN1HPGDNPSR1L3MBTL1 | |
| SCHEMBL5061949 | 0.80 | KMT2A (0.53) | KMT2AMEN1HPGDNPSR1L3MBTL1 | |
| SCHEMBL404750 | 0.80 | TDP1 (0.53) | HTTATMTDP1KCNMA1MAPT | |
| SCHEMBL32667924 | 0.79 | HCAR3 (0.63) | KMT2AMEN1HPGDNPSR1ALDH1A1 | |
| SCHEMBL1645187 | 0.79 | SLC6A4 (0.64) | KMT2AMEN1HPGDL3MBTL1HTT | |
| SCHEMBL4817687 | 0.78 | ATM (0.52) | HPGDL3MBTL1ATMTDP1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187803-A | The synthetic method of the amides compound that a kind of phosphorus oxychloride promotes | 中国人民解放军63975部队 | 2016-12-07 | — | — | CN | disclosed |