Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399328 | 0.87 | ALDH1A1 (0.54) | HPGDSMN1; SMN2KMT2AMEN1NPSR1 | |
| SCHEMBL11687524 | 0.86 | HPGD (0.49) | HPGDCYP1A2CYP3A4CYP2C19FLT1 | |
| Hydrochloric Acid SCHEMBL11687533 | 0.85 | HPGD (0.49) | HPGDCYP1A2CYP3A4CYP2C19FLT1 | |
| SCHEMBL16670537 | 0.83 | HPGD (0.48) | HPGDCYP1A2CYP3A4CYP2C19FLT1 | |
| SCHEMBL848335 | 0.81 | HPGD (0.56) | HPGDCYP1A2CYP3A4CYP2C19FLT1 | |
| SCHEMBL29758067 | 0.81 | HPGD (0.56) | HPGDCYP1A2CYP3A4CYP2C19FLT1 | |
| SCHEMBL11301098 | 0.81 | HPGD (0.59) | HPGDCYP1A2CYP3A4CYP2C19FLT1 | |
| SCHEMBL135219 | 0.81 | ALDH1A1 (0.53) | HPGDSMN1; SMN2KMT2AMEN1NPSR1 | |
| SCHEMBL28114926 | 0.81 | KMT2A (0.50) | HPGDSMN1; SMN2KMT2AMEN1NPSR1 | |
| SCHEMBL2204732 | 0.80 | HPGD (0.57) | HPGDCYP1A2CYP3A4CYP2C19FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187803-A | The synthetic method of the amides compound that a kind of phosphorus oxychloride promotes | 中国人民解放军63975部队 | 2016-12-07 | — | — | CN | disclosed |