Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 10/20 | 0.67 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.56 |
| ▸ | KDM6B | O15054 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | CISD1 | Q9NZ45 | 6/20 | 0.52 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.48 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.48 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824061 | 0.95 | PLK1 (0.64) | PLK1PLK3KDM6BKDM4CCISD1 | |
| SCHEMBL28109945 | 0.88 | PLK1 (0.67) | PLK1PLK3CISD1TRPM2HCAR3 | |
| SCHEMBL28293669 | 0.86 | PLK1 (0.54) | PLK1PLK3KDM6BKDM4CCISD1 | |
| SCHEMBL1884483 | 0.84 | CISD1 (0.63) | PLK1KDM6BKDM4CCISD1HCAR3 | |
| SCHEMBL28293667 | 0.84 | PLK1 (0.52) | PLK1PLK3KDM6BKDM4CCISD1 | |
| SCHEMBL22097725 | 0.84 | HCAR3 (0.60) | PLK1PLK3KDM6BKDM4CCISD1 | |
| SCHEMBL3781973 | 0.84 | PLK1 (0.62) | PLK1KDM6BKDM4CCISD1HCAR3 | |
| SCHEMBL5386530 | 0.82 | PLK1 (0.58) | PLK1PLK3KDM4CTRPM2 | |
| SCHEMBL29223566 | 0.81 | ALDH1A1 (0.61) | PLK1PLK3GUCY1A1GUCY1B1 | |
| SCHEMBL27736211 | 0.81 | KDM6B (0.52) | PLK1KDM6BKDM4CCISD1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146414-A | Quinazoline diones analog derivative and its production and use | 浙江大学 | 2016-11-23 | — | — | CN | disclosed |