Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67938 | 0.94 | MEN1 (0.59) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL10029272 | 0.93 | POLB (0.58) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL25402465 | 0.93 | POLB (0.61) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL2154214 | 0.91 | ALDH1A1 (0.58) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL14477491 | 0.91 | MEN1 (0.66) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL68457 | 0.91 | POLB (0.60) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL8006616 | 0.90 | POLB (0.59) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL7003272 | 0.89 | POLB (0.60) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL28725903 | 0.88 | POLB (0.63) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL14981830 | 0.88 | POLB (0.54) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106176250-B | Tooth adhesive system based on new hydrophobic adhesion concept | 浙江大学 | 2020-06-23 | — | — | CN | claimed |
| CN-106137774-B | Pit and fissure sealant based on tooth surface hydrophobization concept | 浙江大学 | 2020-04-17 | — | — | CN | claimed |
| CN-106176250-B | Tooth adhesive system based on new hydrophobic adhesion concept | 浙江大学 | 2020-06-23 | — | — | CN | disclosed |
| CN-106137774-B | Pit and fissure sealant based on tooth surface hydrophobization concept | 浙江大学 | 2020-04-17 | — | — | CN | disclosed |
| CN-106176250-A | Tooth bonding agent system based on hydrophobic bonding new concept | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |