Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413862 | 0.92 | ALDH1A1 (0.43) | HPRT1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL137986 | 0.92 | ALDH1A1 (0.43) | HPRT1ALDH1A1HPGDKDM4EHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28277205 | 0.90 | ALDH1A1 (0.42) | HPRT1ALDH1A1HPGDKDM4EHSD17B10 | |
| Water SCHEMBL28231159 | 0.90 | ALDH1A1 (0.42) | HPRT1ALDH1A1HPGDKDM4EHSD17B10 | |
| Thioxanthene SCHEMBL27964760 | 0.81 | HPRT1 (0.39) | HPRT1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL27714344 | 0.81 | HPGD (0.36) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL30579631 | 0.75 | HPRT1 (0.61) | HPRT1ALDH1A1HPGDHSD17B10CYP2A6 | |
| Thianthrene SCHEMBL27426419 | 0.73 | HPRT1 (0.44) | HPRT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL22721229 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4ECYP2A6TSHR | |
| SCHEMBL610943 | 0.72 | LMNA (0.44) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349212-A | Naphtho-thioxanthene derivative as well as preparation method and application thereof | 长春海谱润斯科技有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-106349212-A | Naphtho-thioxanthene derivative as well as preparation method and application thereof | 长春海谱润斯科技有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-106336408-A | Naphthothioxanthene derivative and preparation method and application thereof | 长春海谱润斯科技有限公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-106336408-A | Naphthothioxanthene derivative and preparation method and application thereof | 长春海谱润斯科技有限公司 | 2017-01-18 | — | — | CN | disclosed |