Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123916 | 0.72 | APLNR (0.36) | ABCB11ALDH1A1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL29123911 | 0.72 | ALDH1A1 (0.33) | ABCB11ALDH1A1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL29123912 | 0.72 | MIF (0.38) | ABCB11ALDH1A1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL28879957 | 0.69 | LOXL2 (0.46) | LOXL2PNMTST14TAAR1HRH3 | |
| SCHEMBL29875484 | 0.69 | LOXL2 (0.46) | LOXL2PNMTST14TAAR1HRH3 | |
| SCHEMBL28115349 | 0.69 | APLNR (0.45) | ALDH1A1CYP1A2CYP3A4HPGDHSD17B10 | |
| SCHEMBL27833135 | 0.69 | P2RY6 (0.35) | P2RY6 | |
| SCHEMBL16192966 | 0.69 | P2RY6 (0.68) | P2RY6LOXL2ST14TAAR1HRH3 | |
| SCHEMBL21983780 | 0.68 | MIF (0.41) | TAAR1ABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL27820374 | 0.67 | P2RY6 (0.41) | P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187943-B | A kind of preparation method of 1,4- benzothiazines | 温州大学 | 2018-06-15 | — | — | CN | disclosed |
| CN-106187943-A | A kind of preparation method of 1,4 benzothiazines | 温州大学 | 2016-12-07 | — | — | CN | disclosed |