Propionitrile

Propionitrile

SCHEMBL28115464

CCC#N.N/C(=C\C(=O)O)C(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MCL1 Q07820 1/20 0.34
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionitrile SCHEMBL27934880 0.81 ALDH1A1 (0.39) ALDH1A1MEN1KMT2AMCL1KDM4E
SCHEMBL4544097 0.79
SCHEMBL4438376 0.79
SCHEMBL4544101 0.79
Propionitrile SCHEMBL27668043 0.77
Propionitrile SCHEMBL9729826 0.72 MEN1 (0.52) ALDH1A1MEN1KMT2AMCL1TSHR
Propionitrile SCHEMBL9729817 0.72 MEN1 (0.52) ALDH1A1MEN1KMT2AMCL1TSHR
Maleic Acid SCHEMBL27748379 0.72 MEN1 (0.56) ALDH1A1MEN1KMT2ATSHR
Maleic Acid SCHEMBL27748381 0.72 MEN1 (0.56) ALDH1A1MEN1KMT2ATSHR
Acetamide SCHEMBL28230092 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106492218-A Purposes of the aminopropionitrile in medicine is prepared 清华大学 2017-03-15 CN disclosed