⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544097 | 1.00 | — | — | |
| SCHEMBL4438376 | 1.00 | — | — | |
| SCHEMBL10686269 | 0.80 | — | — | |
| SCHEMBL8068005 | 0.80 | — | — | |
| SCHEMBL28929333 | 0.80 | — | — | |
| SCHEMBL10686260 | 0.80 | — | — | |
| Propionitrile SCHEMBL28115464 | 0.79 | ALDH1A1 (0.38) | — | |
| SCHEMBL20338617 | 0.77 | LDHA (0.33) | — | |
| SCHEMBL468412 | 0.75 | — | — | |
| SCHEMBL468414 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103886925-A | Recovering method for uranium and fluorine in uranium hexafluoride alkali absorption solution waste liquid | UNIV LANGZHOU | 2014-06-25 | — | — | CN | claimed |
| EP-1913942-B1 | The use of fumaric acid derivatives for inhibition of PGF-induced thymidine uptake of bronchial smooth muscle cells and for inhibition of bronchial smooth cells proliferation | BIOGEN IDEC INTERNAT GMBH (CH) | 2009-11-11 | — | — | EP | claimed |
| EP-1663197-B1 | THE USE OF FUMARIC ACID DERIVATIVES FOR TREATING CARDIAC INSUFFICIENCY, AND ASTHMA | FUMAPHARM AG (CH) | 2007-12-05 | — | — | EP | claimed |
| EP-0560019-B1 | Process for the preparation of dialkyl 2,3-pyridinedicarboxylate and derivatives thereof from an alpha, beta-unsaturated oxime and an aminobutenedioate | AMERICAN CYANAMID CO (US) | 1996-04-24 | — | — | EP | claimed |
| EP-0560019-A1 | Process for the preparation of dialkyl 2,3-pyridinedicarboxylate and derivatives thereof from an alpha, beta-unsaturated oxime and an aminobutenedioate | AMERICAN CYANAMID COMPANY (US) | 1993-09-15 | — | — | EP | claimed |
| US-5227491-A | Process for the preparation of dialkyl 2,3-pyridinedicarboxylate and derivatives thereof from an α,β-unsaturated oxime and an aminobutenedioate | AMERICAN CYANAMID COMPANY (US) | 1993-07-13 | — | — | US | claimed |
| EP-0452094-A2 | A method of the preparation of N-hydroxy aspartic acid derivate | HOECHST CELANESE CORPORATION (US) | 1991-10-16 | — | — | EP | claimed |
| JP-6128205-A | — | — | None | — | — | JP | disclosed |
| JP-6056787-A | — | — | None | — | — | JP | disclosed |
| CN-115536647-A | Preparation method and application of green and efficient hydantoin molecule derivative | 聊城金歌合成材料有限公司 | 2022-12-30 | — | — | CN | disclosed |
| US-10772330-B2 | Controlled release N-halamine polymers for water decontamination and detoxification | YISSUM RESEARCH DEVELOPMENT COMPANY (IL) | 2020-09-15 | — | — | US | disclosed |
| CN-110191898-A | CD 33-specific chimeric antigen receptor | 英特瑞克斯顿股份有限公司 | 2019-08-30 | — | — | CN | disclosed |
| EP-3473098-A1 | COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF | Gorbunov, Sergei Valeryevich (RU) | 2019-04-24 | — | — | EP | disclosed |
| EP-0560019-A1 | Process for the preparation of dialkyl 2,3-pyridinedicarboxylate and derivatives thereof from an alpha, beta-unsaturated oxime and an aminobutenedioate | AMERICAN CYANAMID COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0560019-A1 | Process for the preparation of dialkyl 2,3-pyridinedicarboxylate and derivatives thereof from an alpha, beta-unsaturated oxime and an aminobutenedioate | AMERICAN CYANAMID COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5227491-A | Process for the preparation of dialkyl 2,3-pyridinedicarboxylate and derivatives thereof from an α,β-unsaturated oxime and an aminobutenedioate | AMERICAN CYANAMID COMPANY (US) | 1993-07-13 | — | — | US | disclosed |
| US-5227491-A | Process for the preparation of dialkyl 2,3-pyridinedicarboxylate and derivatives thereof from an α,β-unsaturated oxime and an aminobutenedioate | AMERICAN CYANAMID COMPANY (US) | 1993-07-13 | — | — | US | disclosed |
| US-5208342-A | Hydrolysis and dehydration | HOECHST CELANESE CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0452094-A2 | A method of the preparation of N-hydroxy aspartic acid derivate | HOECHST CELANESE CORPORATION (US) | 1991-10-16 | — | — | EP | disclosed |
| US-3719520-A | SYNTHETIC LEATHER | KYOWA HAKKO KOGYO KK | 1973-03-06 | — | — | US | disclosed |