SCHEMBL28115511

SCHEMBL28115511

C=CCNC(=O)C(F)(F)F.CC1CCCC[Si]1(C)C

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
NPSR1 Q6W5P4 2/20 0.37
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27675990 0.83 KMT2A (0.40) ALDH1A1NPSR1KMT2ASMN1; SMN2HSD17B10
Trifluoroacetic Acid SCHEMBL28657400 0.75 GAA (0.32) SMN1; SMN2HSD17B10
SCHEMBL236402 0.74 ALDH1A1 (0.50) ALDH1A1KMT2ASMN1; SMN2LMNAPOLB
Trifluoroacetamide SCHEMBL27294990 0.74 EPHX1 (0.33) SMN1; SMN2HSD17B10
Trifluoroacetamide SCHEMBL28303100 0.74 EPHX1 (0.33) SMN1; SMN2HSD17B10
SCHEMBL27851597 0.72
Propane SCHEMBL28151452 0.69
Acetic Acid SCHEMBL27395973 0.68 GAA (0.36) SMN1; SMN2HSD17B10
Oxalic Acid SCHEMBL28847398 0.68 GAA (0.36) SMN1; SMN2HSD17B10
Urea SCHEMBL27294645 0.68 EPHX1 (0.39) SMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106200256-A Phasing back blank mask and photomask 株式会社S&STECH 2016-12-07 CN disclosed