SCHEMBL236402

SCHEMBL236402

C=CCNC(=O)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
POLB P06746 1/20 0.50
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
TSHR P16473 2/20 0.46
MAPT P10636 1/20 0.46
CA3 P07451 2/20 0.43
CA5A P35218 2/20 0.43
CA5B Q9Y2D0 2/20 0.43
CA2 P00918 2/20 0.43
CA12 O43570 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
EPHX1 P07099 1/20 0.41
FAAH O00519 1/20 0.38
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12319214 0.82 SMN1; SMN2 (0.43) ALDH1A1SMN1; SMN2POLBKMT2ATSHR
SCHEMBL2408985 0.82 SMN1; SMN2 (0.43) ALDH1A1SMN1; SMN2POLBKMT2ATSHR
SCHEMBL9030133 0.81 CA3 (0.60) ALDH1A1SMN1; SMN2POLBKMT2AMEN1
SCHEMBL28659651 0.80 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2KMT2AMEN1TSHR
SCHEMBL18262004 0.80 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2POLBKMT2AMEN1
SCHEMBL18262005 0.80 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2POLBKMT2AMEN1
SCHEMBL29067006 0.79 TSHR (0.41) ALDH1A1SMN1; SMN2KMT2ATSHRMAPT
SCHEMBL9340830 0.78 CA3 (0.56) ALDH1A1SMN1; SMN2POLBKMT2AMEN1
SCHEMBL6834542 0.77 CA2 (0.37) ALDH1A1SMN1; SMN2POLBKMT2AMEN1
SCHEMBL9430552 0.77 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2POLBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480902-B Intelligent encapsulated acid and use method thereof 四川省帕提科斯能源科技有限公司 2023-03-28 CN claimed
CN-112300773-B Intelligent encapsulated oxidant and application method thereof 西南石油大学 2023-03-28 CN claimed
CN-112480902-A Intelligent encapsulated acid and use method thereof 四川省帕提科斯能源科技有限公司 2021-03-12 CN claimed
US-20080054171-A1 Target for Laser Desorption/Ionisation Mass Spectrometry PHYSIKALISCHES BURO STEINMULLER GMBH 2008-03-06 US claimed
CN-1249111-C Prepn process of modified styrene-acrylic emulsion UNIV JIANGHAN (CN) 2006-04-05 CN claimed
US-20050090486-A1 Trisubstituted pyrimidines BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-04-28 US claimed
CN-1486996-A Prepn process of modified styrene-acrylic emulsion 江汉大学 2004-04-07 CN claimed
US-20030134838-A1 Trisubstituted pyrimidines BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-17 US claimed
JP-3086897-A None JP disclosed
EP-4748941-A2 NUCLEOSIDES AND NUCLEOTIDES WITH 3 -HYDROXY BLOCKING GROUPS Illumina Cambridge Limited (GB) 2026-05-27 EP disclosed
EP-3902814-B1 NUCLEOSIDES AND NUCLEOTIDES WITH 3'-HYDROXY BLOCKING GROUPS AND THEIR USE IN POLYNUCLEOTIDE SEQUENCING METHODS ILLUMINA CAMBRIDGE LTD (GB) 2026-04-08 EP disclosed
US-20250236635-A1 METHODS OF SEQUENCING USING NUCLEOTIDES WITH 3' ACETAL BLOCKING GROUP ILLUMINA CAMBRIDGE LIMITED (GB) 2025-07-24 US disclosed
US-20250146066-A1 NUCLEOTIDES WITH A 3' AOM BLOCKING GROUP ILLUMINA CAMBRIDGE LIMITED (GB) 2025-05-08 US disclosed
US-12286453-B2 Methods of sequencing using nucleotides with 3′ acetal blocking group ILLUMINA CAMBRIDGE LIMITED (GB) 2025-04-29 US disclosed
EP-0194545-A2 Labelling of oligonucleotides MOLECULAR DIAGNOSTICS, INC. (US) 1986-09-17 EP disclosed
EP-0192197-A2 Fast and specific immobilization of nucleic acids to solid supports MOLECULAR DIAGNOSTICS, INC. (US) 1986-08-27 EP disclosed
EP-0135587-A4 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. MOLECULAR BIOSYSTEMS INC (US) 1986-04-02 EP disclosed
EP-0135587-A1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. MOLECULAR BIOSYSTEMS INC (US) 1985-04-03 EP disclosed
WO-1984003285-A1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS MOLECULAR BIOSYSTEMS INC (US) 1984-08-30 WO disclosed
US-4154756-A HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1979-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250146066-A1 NUCLEOTIDES WITH A 3' AOM BLOCKING GROUP NT5C3B, NSUN2, RNMT ALDH1A1 899/4885SMN1; SMN2 3692/4885POLB 76/4885
US-20030134838-A1 Trisubstituted pyrimidines APP, PSEN1, BACE1 ALDH1A1 753/4885SMN1; SMN2 131/4885POLB 1630/4885
US-20250236635-A1 METHODS OF SEQUENCING USING NUCLEOTIDES WITH 3' ACETAL BLOCKING GROUP RNGTT, NSUN2, NT5C3B ALDH1A1 657/4885SMN1; SMN2 683/4885POLB 27/4885
US-20050090486-A1 Trisubstituted pyrimidines APP, BACE1, PSEN1 ALDH1A1 681/4885SMN1; SMN2 178/4885POLB 1148/4885
US-12286453-B2 Methods of sequencing using nucleotides with 3′ acetal blocking group RNGTT, NSUN2, NT5C3B ALDH1A1 640/4885SMN1; SMN2 756/4885POLB 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.