Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | AHCY | P23526 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283124 | 1.00 | L3MBTL1 (0.41) | L3MBTL1MAPK1ALDH1A1GAATSHR | |
| SCHEMBL11275393 | 0.80 | AHCY (0.60) | ALDH1A1ADORA2AAHCYADORA1 | |
| SCHEMBL11282682 | 0.80 | AHCY (0.60) | ALDH1A1ADORA2AAHCYADORA1 | |
| SCHEMBL11280448 | 0.78 | ADORA2A (0.37) | ALDH1A1ADORA2AAHCYADORA1 | |
| SCHEMBL28115671 | 0.75 | ADORA2A (0.56) | ALDH1A1SMN1; SMN2ADORA2AAHCYADORA1 | |
| SCHEMBL10569301 | 0.73 | KMT2A (0.49) | ALDH1A1GAATSHRMEN1KMT2A | |
| SCHEMBL10570833 | 0.73 | KMT2A (0.49) | ALDH1A1GAATSHRMEN1KMT2A | |
| SCHEMBL10569307 | 0.73 | KMT2A (0.49) | ALDH1A1GAATSHRMEN1KMT2A | |
| SCHEMBL11132662 | 0.71 | ALDH1A1 (0.54) | L3MBTL1MAPK1ALDH1A1GAATSHR | |
| SCHEMBL28025689 | 0.69 | ALDH1A1 (0.46) | ALDH1A1ADORA2AAHCYADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052964-A1 | Adenine derivatives possessing pharmacological activity | BEECHAM GROUP PLC (GB) | 1982-06-02 | — | — | EP | disclosed |